Hvac Coronavirus Confrontation

  • It is likely, but not yet shown, that COVID19 could be spread through the air.
  • Air cleaning can help mitigate disease transmission.
  • Options for air cleaning include:
    • HVAC systems
    • In-Room devices
  • Technologies that can be effective include:
    • Mechanical Air Filters
    • Electronic Air Filters/Air Cleaners
    • UV-C Systems
    • Other Emerging Technologies
  • Care and professional judgement should be taken to understand choices for filtration and air disinfection, pros and cons of each and impact(s) on existing buildings systems.

Information on these pages is provided as a service to the public. While every effort is made to provide accurate and reliable information, this is advisory, is provided for informational purposes only. These are not intended and should not be relied upon as official statements.

Reference: ASHRAE (The American Society of Heating, Refrigerating and Air-Conditioning Engineers)

Modes of Transmission

  • SARS-CoV-2, the virus that causes COVID-19, is thought to spread mainly from person-to-person through respiratory droplets and aerosols.
  • Infectious respiratory droplets are produced when an infected person coughs or sneezes.
    • Droplets can land in the mouths or noses of nearby people.
    • Droplets can land on surfaces and be spread through contact with contaminated surfaces.
    • When in close contact with an infected person, droplets can be inhaled into the lungs.
  • Airborne transmission in some circumstances seems probable. 
  • The SARS-CoV-2 virus may be aerosolized by flushing the toilet.

Airborne Transmission

ASHRAE Statement on airborne transmission of SARS-CoV-2

  • Transmission of SARS-CoV-2 through the air is sufficiently likely that airborne exposure to the virus should be controlled. Changes to building operations, including the operation of HVAC systems can reduce airborne exposures.

ASHRAE Statement on operation of heating, ventilating, and air-conditioning systems to reduce SARS-CoV-2 transmission

  • Ventilation and filtration provided by heating, ventilating, and air-conditioning systems can reduce the airborne concentration of SARS-CoV-2 and thus the risk of transmission through the air. Unconditioned spaces can cause thermal stress to people that may be directly life threatening and that may also lower resistance to infection. In general, disabling of heating, ventilating, and air-conditioning systems is not a recommended measure to reduce the transmission of the virus.

Transmission through Air in Toilet Rooms

Studies have shown that toilets can be a risk of generating airborne droplets and droplet residues that could contribute to transmission of pathogens.

  • Keep toilet room doors closed, even when not in use.
  • Put the toilet seat lid down, if there is one, before flushing.
  • Vent separately where possible (e.g. turn exhaust fan on if vented directly outdoors and run fan continuously).
  • Keep bathroom windows closed if open windows could lead to re-entrainment of air into other parts of the building.

Facilities/Maintenance – PPE Basics

  • Refer to CDC Guidance on PPE use.
  • N95 filtering facepiece respirators
    • Protects the wearer from respiratory droplets AND aerosols.
    • Can be an effective tool for worker protection with proper use.
    • Require fit testing and a medical clearance to wear for work.
    • Tested for efficiency against 0.3 micrometer airborne particles.
    • Certified to filter at least 95% of these particles.
    • Generally disposed of after each use, but pandemic has resulted in limited supplies. CDC issued Strategies to Optimize the Supply of PPE
  • Silicone half mask respirators with N95 cartridges (or better) can be used instead of filtering facepiece respirators.
  • Eye Protection
    • Safety glasses (side shields preferred)
    • Goggles
    • Face shields
  • Disposable Gloves
    • Can be vinyl, rubber or nitrile
    • Double gloves reduces likelihood of cuts/punctures
    • Can be worn under work gloves if necessary
  • Disposable coveralls, gowns and/or shoe covers can be worn to enhance overall protection.
  • After maintenance activities, wash hands with soap and water or use an alcohol-based hand sanitizer. Change clothes if soiled.

HVAC System Maintenance and Filter Replacement during the COVID-19 Pandemic

  • For HVAC systems suspected to be contaminated with SARS-CoV-2, it is not necessary to suspend HVAC system maintenance, including filter changes, but additional safety precautions are warranted.
  • The risks associated with handling filters contaminated with coronaviruses in ventilation systems under field-use conditions have not been evaluated.
  • Workers performing maintenance and/or replacing filters on any ventilation system with the potential for viral contamination should wear appropriate personal protective equipment (PPE):
    • A properly-fitted respirator (N95 or higher)
    • Eye protection (safety glasses, goggles, or face shield)
    • Disposable gloves
  • Consider letting the filter load up further than usual to reduce frequency of filter changes.
    • Don’t let pressure drop increase enough to disrupt room pressure differentials.
    • Confirm filters remain snug in their frames.
  • When feasible, filters can be disinfected with a 10% bleach solution or another appropriate disinfectant, approved for use against SARS-CoV-2, before removal. Filters (disinfected or not) can be bagged and disposed of in regular trash.
  • When maintenance tasks are completed, maintenance personnel should immediately wash their hands with soap and water or use an alcohol-based hand sanitizer.

Mechanical Air Filters

  • Filters consist of media with porous structures of fibers or stretched membrane material to remove particles from airstreams.
  • Some filters have a static electrical charge applied to the media to increase particle removal. Since the efficiency of these filters often drops off over months of initial use, a MERV-A value, if available, will reflect the actual minimum efficiency better than a standard MERV value. 
  • The fraction of particles removed from air passing through a filter is termed “filter efficiency” and is provided by the Minimum Efficiency Reporting Value (MERV) under standard conditions.
    • MERV ranges from 1 to 16; higher MERV = higher efficiency
    • MERV ≥13 (or ISO equivalent) are efficient at capturing airborne viruses
    • MERV 14 (or ISO equivalent) filters are preferred
    • High efficiency particulate air (HEPA) filters are more efficient than MERV 16 filters.
  • Some filters have a static electrical charge applied to the media to increase particle removal. Since the efficiency of these filters often drops off over months of initial use, a MERV A value, if available, will reflect the actual minimum efficiency better than a standard MERV value.
  • Increased filter efficiency generally results in increased pressure drop through the filter. Ensure HVAC systems can handle filter upgrades without negative impacts to pressure differentials and/or air flow rates prior to changing filters.
  • Generally, particles with an aerodynamic diameter around 0.3 μm are most penetrating; efficiency increases above and below this particle size.
  • Overall effectiveness of reducing particle concentrations depends on several factors:
    • Filter efficiency
    • Airflow rate through the filter
    • Size of the particles
    • Location of the filter in the HVAC system or room air cleaner

ASHRAE Standard 52.2-2017 — Minimum Efficiency Reporting Value (MERV)

ASHRAE MERV vs. ISO 16890 Ratings

*MERV-A will give closer results. Charged media filters usually show a drop-off in efficiency with use. ISO 16890 captures this with an IPA condition step. ASHRAE 52.2 can capture this drop if the test is done with the optional Appendix J which gives the MERV-A. Thus the MERV and the ePM ratings do not reflect the same testing. For charged media, the MERV will likely make the filter appear more efficient than the ePM rating.

HEPA Filters

  • By definition, true HEPA filters are at least 99.97% efficient at filtering 0.3 μm mass median diameter (MMD) particles in standard tests.
  • Most penetrating particle size may be smaller than 0.3 μm, so filtration efficiency of most penetrating particles can be slightly lower.
  • HEPA filter efficiency is better than MERV 16.
  • HEPA filters may not be an appropriate option for some into HVAC systems due to high pressure drops and the likelihood that systems will need new filter racks to allow sufficient sealing to prevent filter bypass.
  • To function properly, HEPA filters must be sealed properly in filter racks.
  • Filters are often delicate and require careful handling to prevent damage and preserve performance.
  • HEPA filters can be located in HVAC systems or in:
    • In-Room or Portable HEPA Machines
    • Pre-Assembled Systems
    • Ad Hoc Assemblies 

Electronic Air Filters

  • Include a wide variety of electrically-connected air-cleaning devices designed to remove particles from airstreams.
  • Removal typically occurs by electrically charging particles using corona wires or by generating ions (e.g., pin ionizers), and:
    • Collecting particles on oppositely charged plates (precipitators, ESP),or
    • Charged particles’ enhanced removal by a mechanical air filter, or
    • Charged particles’ deposition on room surfaces.
  • The fraction of particles removed from air by an electronic filter is termed “removal efficiency.”
  • Overall effectiveness of reducing particle concentrations depends on:
    • Removal efficiency
    • Airflow rate through the filter
    • Size and number of particles
    • Location of the filter in the HVAC system
    • Maintenance and cleanliness of electronic filter components
  • It is critical to wipe the wires in electrostatic precipitators as silicone buildup reduces efficiency.
  • Always follow manufacturer’s instructions when using electronic air filters.

Gas-Phase Air Cleaners

  • Gas-phase air cleaners are those used to remove ozone, volatile organic compounds and odors from the air.
  • Most contain sorbent materials such as carbon (e.g., activated charcoal).
  • While there may be exceptions, most sorbent beds alone are not generally efficient at removing viruses from airstreams.
  • Carbon/sorbent impregnated fiber filters will remove particles; check for a MERV rating to show efficiency just as you do with standard particulate filters.

Ultraviolet Energy (UV-C)

  • Ultraviolet energy inactivates viral, bacterial, and fungal organisms so they are unable to replicate and potentially cause disease.
  • The entire UV spectrum is capable of inactivating microorganisms, but UV-C energy (wavelengths of 100 – 280 nm) provides the most germicidal effect, with 265 nm being the optimum wavelength.
  • The majority of modern UVGI lamps create UV-C energy with an electrical discharge through a low-pressure gas (including mercury vapor) enclosed in a quartz tube, similar to fluorescent lamps.
  • Roughly 95% of the energy produced by these lamps is radiated at a near-optimal wavelength of 253.7 nm.
  • UV-C light-emitting diodes (LEDs) are emerging for use.
  • Types of disinfection systems using UV-C energy:
    • In-duct air disinfection
    • Upper-air disinfection
    • In-duct surface disinfection
    • Portable room decontamination
  • Requires special PPE to prevent damage to eyes and/or skin from overexposure.
  • The Illuminating Engineering Society (IES) Photobiology Committee published a FAQ on Germicidal Ultraviolet (GUV) specific to the COVID-19 pandemic.


  • Have been common in the UV-A spectrum (315 – 400 nm)
  • LEDs are starting to be produced in the 265 nm range
  • Efficiency is dramatically less than current low-pressure mercury vapor lamps
  • Minimal UV output compared to a low-pressure mercury vapor lamp
  • For equal output, UV-C LEDs are more expensive than current low-pressure mercury vapor lamps
  • Limited availability; not yet practical for commercial HVAC applications

UV-C In-Duct Air Disinfection

  • Banks of UV-Lamps installed inside HVAC systems or associated ductwork.
  • Requires high UV doses to inactivate microorganisms on-the-fly as they pass through the irradiated zone due to limited exposure time.
    • Minimum target UV dose of 1,500 µW•s/cm2 (1,500 µJ/cm2)
    • Systems typically designed for 500 fpm moving airstream.
    • Minimum irradiance zone of two feet
    • Minimum UV exposure time of 0.25 second.
  • Should always be coupled with mechanical filtration.
    • MERV 8 filter for dust control
    • Highest practical MERV filter recommended
    • Enhanced overall air cleaning with increased filter efficiency

UV-C Upper-Air Disinfection

  • UV fixtures mounted in occupied spaces at heights of 7 feet and above.
  • Consider when:
    • No mechanical ventilation
    • Limited mechanical ventilation
    • Congregate settings and other high-risk areas
    • Economics/other
  • Requires low UV-reflectivity of walls and ceilings
  • Ventilation should maximize air mixing
  • Use supplemental fans where ventilation is insufficient

UV-C In-Duct Surface Disinfection

  • Banks of UV-Lamps installed inside HVAC systems, generally focused on:
    • Cooling coils
    • Drain pans
    • Other wetted surfaces
  • UV irradiance can be lower than in-duct air disinfection systems due to long exposure times.
  • Goals are:
    • Even distribution of UV energy across the coil face
    • Generally, 12 to 36 inches from the coil face
    • Operated 24/7

UV-C Portable Room Decontamination

  • For surface decontamination
  • Portable, fully automated units; may use UV-C lamps or Pulsed Xenon technology
  • Settings for specific pathogens such as MRSA, C. difficile, both of which are harder to inactivate than coronaviruses.
    • >99.9% reduction of vegetative bacteria within 15 minutes
    • 99.8% for C.difficile spores within 50 minutes

   (Rutala et al. 2010)

Photocatalytic Oxidation (PCO) and Dry Hydrogen Peroxide (DHP)

  • Consists of a pure or doped metal oxide semiconductor material
    • Most Common Photocatalyst is Ti02 (titanium dioxide)
  • Activated by a UV light source
    • UV-A (400-315nm)
    • UV-C (280-200nm
    • UV-V (under 200nm) Ozone can be formed at UV-V wavelengths
  • Light mediated, redox reaction of gases and biological particles absorbed on the surface
  • Some units claim disinfection from gaseous hydrogen peroxide.
  • Possible by-products formed by incomplete oxidizing.
  • Some air cleaners using PCO remove harmful contaminants to levels below limits for reducing health risks set by recognized cognizant authorities.
  • Some are ineffective in reducing concentrations significantly; manufacturer data should be considered carefully.

Bipolar Ionization/Corona Discharge / Needlepoint Ionization and Other Ion or Reactive Oxygen Air Cleaners

  • Air cleaners using reactive ions and/or reactive oxygen species (ROS) have become prevalent during the COVID-19 pandemic. New devices that are not mentioned elsewhere in this guidance likely fall into this category.
  • Technologies utilize various methods to create reactive ions in air that react with airborne contaminants, including viruses. The design of the systems can be modified to create mixtures of reactive oxygen species (ROS), ozone, hydroxyl radicals and superoxide anions.
  • Systems are reported to range from ineffective to very effective in reducing airborne particulates and acute health symptoms.
  • Convincing scientifically-rigorous, peer-reviewed studies do not currently exist on this emerging technology; manufacturer data should be carefully considered.
  • Systems may emit ozone, some at high levels. Manufacturers are likely to have ozone generation test data.


  • Ozone (O3) is a reactive gas that can disinfect air and surfaces by killing viruses, bacteria, and fungi.
  • Ozone is harmful for health and exposure to ozone creates risk for a variety of symptoms and diseases associated with the respiratory tract.
  • ASHRAE’s Environmental Health Committee issued an emerging issue brief suggesting “safe ozone levels would be lower than 10 ppb” and that “the introduction of ozone to indoor spaces should be reduced to as low as reasonably achievable (ALARA) levels.”
  • Should only be considered for disinfection on unoccupied spaces; it should never be used in occupied spaces.
    • Available scientific evidence shows that, at concentrations that do not exceed public health standards, ozone is generally ineffective in controlling indoor air pollution.
    • Reputable cleaning and restoration companies should be used for effective, safe disinfection of unoccupied spaces.

In-Room or Portable Air Cleaners

  • Device is located in the room where air cleaning is desired. Place air cleaner where air intake and discharge are not impeded (e.g., not near furniture or behind curtains).
  • Air is pulled into the device, and cleaned air is returned to the room. Flexible ductwork can be attached to some devices to allow strategic positioning of intake and/or discharge locations, including discharge outside the room to create pressure differences and/or create clean to less-clean directional airflow.
  • Devices may include any or combinations of air cleaning technologies (filters, sorbents, UV, etc.). Users are advised to carefully determine that the application of the technology is appropriate for their need.
  • Devices are rated by the Association of Home Appliance Manufacturers.
    • The rate of particle removal from air is termed the Clean Air Delivery Rate (CADR), typically in units of cubic feet per minute (CFM).
    • CADR ≈ airflow rate × removal efficiency
  • To reach a desired air exchange rate in air changes per hour (ACH):
    • ACH = CADR (cfm) × 60 (min/hr) ÷ room volume (ft3)

Chemical Disinfectants

  • EPA reviews and registers antimicrobial pesticides, which include disinfectants for use on pathogens like SARS-CoV-2
  • Carefully read product labels and use as directed.
  • Most products have a required contact or dwell time, which is the amount of time a surface must remain wet to kill a certain pathogen.
  • Applying a product in a way that does not align with its intended use may render the product less effective.
  • Products on EPA List N have not been tested specifically against SARS-CoV-2, however the EPA expects them to kill the virus because they:
    • Demonstrate effectiveness against a harder-to-kill virus; or
    • Demonstrate efficacy against another type of human coronavirus similar to SARS-CoV-2.
  • All surface disinfectants on List N can be used to kill viruses on surfaces such as counters and doorknobs.
  • Because SARS-CoV-2 is a new virus, this pathogen is not yet readily available for use in commercial laboratory testing of disinfectant product effectiveness at killing that specific virus.

Vaporized Hydrogen Peroxide (VHP)

  • Liquid hydrogen peroxide (H2O2) is vaporized and the vapor fills the space to disinfect all exposed surfaces.
  • Space MUST be unoccupied during VHP treatment.
  • Requires spaces to be sealed, including all doorways, plumbing/electrical penetrations and HVAC supply and return vents, to prevent vapor from escaping.
  • After prescribed exposure times, remaining H2O2 vapor is scrubbed from space and converted ack to oxygen and water before space can be safely reoccupied.
  • The effectiveness and safety of VHP when generated inside active HVAC ducts and occupied spaces has not been rigorously studied.
  • VHP is hazardous at high concentrations, and lengthy exposure is often necessary to inactivate bacteria and viruses in sealed spaces.

Pulsed Xenon (Pulsed UV)

  • High-powered UV lamps (generally containing xenon gas) used in rapid pulses of intense energy.
  • Emits a broad brand of visible and ultraviolet wavelengths, with a significant fraction in the UV-C band.
    • Uses significantly higher power outputs that usual UV-C techniques.
    • Inactivates viruses, bacteria and fungi using the same mechanisms as standard UV-C systems.
  • Typically used for healthcare surface disinfection, but can be used in HVAC systems for air and surface disinfection.

405 nm Visible Light

  • Sometimes referred to a “Near UV,” although not in the UV spectrum.
  • Generally integrated into standard room lighting systems.
  • Kills bacteria and fungi via different mechanism than UV-C.
    • Targets and excites naturally-occurring porphyrin molecules inside organisms, creating reactive oxygen species.
    • Reactive oxygen species kill by a mechanism similar to bleach.
  • Effectiveness at killing viruses, including SARS-CoV-2, is not as well documented.
  • Provides continuous disinfection of air and exposed surfaces in occupied spaces.
  • In the FAQs on Germicidal Ultraviolet (GUV), the Illuminating Engineering Society (IES) Photobiology Committee notes that effectiveness is approximately 1000 times less than UV-C and the effective doses are not practical in an occupied environment.

Far Ultraviolet

  • Far UV spectrum is 205 to 230 nm.
  • Some deactivation of bacteria and viruses at the 207 nm and 222 nm range.
  • 222 nm said to effectively penetrate microorganisms 1µm in size and smaller.
  • Unable to fully penetrate larger microorganisms.
  • UV Dose required to inactivate microorganisms is significantly higher at these wavelengths than in the UV-C range.
  • While safety concerns are reduced, can still cause damage to eyes and skin.

Special Precautions

  • Exposure to UV-C energy can cause eye and skin damage.
    • Photokeratitis (inflammation of the cornea)
    • Keratoconjunctivitis (inflammation of the ocular lining of the eye)
  • Symptoms may not be evident until several hours after exposure and may include an abrupt sensation of sand in the eyes, tearing, and eye pain, possibly severe.
    • Symptoms usually appear 6 to 12 hours after UV exposure.
    • Symptoms are fully reversible and resolve within 24 to 48 hours.
  • Maintenance workers should receive special training before working on UV-C systems.
  • If exposures are likely to exceed safe levels, special personal protective equipment (PPE) is required for exposed eyes and skin.
    • Eyewear that blocks UV-C energy
    • Clothing, suits, or gowns known to be nontransparent to UV-C


Aerosol generating procedure (AGP)
Procedures that are likely to induce coughing. Procedures that are believed to generate aerosols and droplets as a source of respiratory pathogens include positive pressure ventilation (bi-level positive airway pressure [BiPAP] and continuous positive airway pressure [CPAP]), endotracheal intubation, airway suction, high-frequency oscillatory ventilation, tracheostomy, chest physiotherapy, nebulizer treatment, sputum induction, and bronchoscopy. AGPs should ideally take place in an airborne infection isolation room (AIIR).
Aerosol, infectious
An infectious aerosol is a system of liquid or solid particles uniformly distributed in a finely divided state through a gas, usually air. (They are small and buoyant enough to behave much like a gas yet they can be filtered out of the gas.)
Aerosol, Short-range transmission
Transmitting disease by inhalation of aerosols near the source. The distance for this transmission has not been studied beyond two meters.
Age of Air
The time that has elapsed after the air enters a space (at any given point.)
Air change rate
Airflow in volume units per hour divided by the building space volume in identical volume units (normally expressed in air changes per hour [ACH or ACPH])
Air irritant
A particle or volatile chemical in air that causes physiological response when in contact with mucosa in the eye, nose, or throat.
Air volume migration
The volume of air that is exchanged during room entry/exit (through a door-way between a room and the area beyond its door)
Air, exhaust
Air removed from a space and discharged outside the building by mechanical or natural ventilation systems.
Air, makeup
Any combination of outdoor and transfer air intended to replace exhaust air and exfiltration.
Air, outdoor
(1) Air outside a building or taken from the outdoors and not previously circulated through the system;
(2) Ambient air that enters a building through a ventilation system, through intentional openings for natural ventilation, or by infiltration.
Air, recirculated
Air removed from a space and reused as supply air.
Air, supply
Air delivered by mechanical or natural ventilation to a space that is composed of any combination of outdoor air, recirculated air, or transfer air.
Air, transfer
Air moved from one indoor space to another.
Airborne droplet nuclei
Small-particle residue (5 µm or smaller) of evaporated droplets containing microorganisms that remain suspended in air and can be dispersed widely by air currents with a room or over a long distance.
Airborne infection isolation room (AIIR)
A room designed with negative pressurization to protect patients and people outside the room from the spread of microorganisms (transmitted airborne droplet nuclei) that infect the patient inside the room.
Airborne infectious agent
An airborne particle that can cause an infection.
Airborne pathogen
An airborne particle that can cause disease.
Airborne transmission
Airborne transmission is defined as “dissemination of either airborne droplet nuclei or small particles in the respirable size range containing infectious agents that remain infective over time and distance.” An important requirement of airborne transmission is that it can occur only at a long distance from the source, according to the CDC.
Air-cleaning system
A device or combination of devices used to reduce the concentration of airborne contaminants, such as microorganisms, dust, fumes, respirable particles, other particulate matter, gases and/or vapors in air. Related term: HEPA Filter.
A room separating an isolation room from a corridor.
Bay (patient)
A space for human occupancy with one hard wall at the headwall and three soft walls.
Particles or droplets suspended in air that consist of or contain biological matter such as bacteria, pollens, fungi, skin flakes, and viruses.
Building air infiltration
Uncontrolled inward leakage of air (that may contain entrained water vapor) through cracks and interstices in any building element and around windows and doors of a building, caused by the pressure effects of wind or the effect of differences in the indoor and outdoor air density.
Clean Air Delivery Rate which is the combined effect of actually how much air is moved through the filter and the filter efficiency.
Community acquired infection
An infection present or incubating in a patient upon admission to a hospital (or who subsequently shelters in place outside the hospital).
Contaminant or Pollutant
Any impurity, any material of an extraneous nature, associated with a chemical, a pharmaceutical preparation, a phuysiologic principle, or an infectious agent.
Contaminant, airborne
An unwanted airborne constituent that may reduce the acceptability of air.
The act of contaminating, especially the introduction of disease germs or infectious material into or on normally sterile objects.
COVID-19 is the short name for “coronavirus disease 2019″
A space intended for human occupancy that has at least one opening and no door and is enclosed on three sides with full height or partial height partitions.
Droplet transmission
Droplet transmission is defined as “respiratory droplets carrying infectious pathogens that transmit infection when they travel directly from the respiratory tract of the infectious individual to susceptible mucosal surfaces of the recipient, generally over short distances, necessitating facial protection.” Close contact involves hand transfer of surface contamination to mouth, nose or eyes, hand washing and gloves being common controls.
Study of the distribution and determinants of disease.
HEPA filter (or absolute filter) 
High efficiency particle air filter with an efficiency of 99.97% removal of particulates larger than 0.30 microns.
Hospital Acquired Infection (HAI)
See Nosocomial infection.
Intensive care rooms (ICU)(also critical care rooms CCU)
Rooms in which the level of patient care and electronic monitoring of patients are greatly increased over conventional patient rooms.
Minimum Efficiency Reporting Value: The fraction of particles removed from air passing through a filter is termed “filter efficiency”
ASHRAE 52.2-2017
Nosocomial infection (or Hospital Acquired Infection [HAI])
An infection that is acquired in a hospital and that was not present or incubating upon admission.
Occupationally acquired infection
An infection acquired while working in a medical care setting.
Opportunistic organism
An ordinarily non-infectious agent that becomes infectious in an immunocompromised host. (any novel organism, especially aerosolized respiratory viruses for which there is no vaccine or herd immunity becomes an opportunistic organism.)
Inflammation of lung tissue.
Personal Preotective Equipment is equipment worn to minimize exposure to hazards that cause serious workplace injuries and illnesses.
A difference in pressure between a space and a reference pressure.
A space enclosed by hard walls and having a door.
Severe Acute Respiratory Syndrome CoronaVirus 2
International Committee on Taxonomy of Viruses (ICTV)
Ultraviolet irradiation.
Ultraviolet germicidal irradiation.
A process of supplying air to or removing air from a space for the purpose of controlling air contaminant levels, humidity, or temperature within the space. Such air may or may not have been conditioned.
Ventilation effectiveness
The ability of a system to remove contaminants generated by a source in a room.


What is the current understanding of COVID-19 transmission through the air?
The current understanding is that COVID-19 is primarily spread through close contact with an infected person, respiratory droplets, and contact with contaminated surfaces. While it is likely that COVID-19 could be spread through the air, this mode of transmission has not been definitively proven. The World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) continue to monitor and update guidance on transmission modes as new research emerges.
How can air cleaning help mitigate disease transmission in buildings?

Air cleaning can help reduce the concentration of airborne pathogens, including viruses, bacteria, and fungi, which can contribute to disease transmission. Effective air cleaning strategies can include a combination of technologies, such as mechanical air filters, electronic air filters/air cleaners, UV-C systems, and other emerging technologies. By removing airborne pathogens, air cleaning can help reduce the risk of disease transmission through the air.

What are the key differences between HVAC systems and in-room devices for air cleaning?

HVAC systems are designed to provide whole-building air cleaning, whereas in-room devices are typically smaller, portable units that clean the air in a specific room or area. HVAC systems often have higher airflow rates and can be more effective at removing airborne pathogens, but may require more complex installation and maintenance. In-room devices, on the other hand, are often easier to install and maintain, but may not be as effective at removing airborne pathogens from the entire building.

How do mechanical air filters compare to electronic air filters/air cleaners for air cleaning?

Mechanical air filters rely on physical barriers to capture airborne particles, whereas electronic air filters/air cleaners use electrostatic charges to attract and capture particles. Mechanical air filters are often more effective at removing larger particles, such as dust and pollen, while electronic air filters/air cleaners are often more effective at removing smaller particles, such as viruses and bacteria. The choice between mechanical and electronic air filters/air cleaners depends on the specific application and the type of airborne pathogens present.

What are the benefits and limitations of UV-C systems for air disinfection?

UV-C systems use ultraviolet light to inactivate airborne pathogens, including viruses and bacteria. The benefits of UV-C systems include their ability to provide rapid and effective air disinfection, with minimal maintenance and energy consumption. However, UV-C systems may not be effective against all types of airborne pathogens, and their effectiveness can be reduced by factors such as airflow rate, humidity, and particle size. Additionally, UV-C systems may not remove airborne particles, only inactivate them.

What are some emerging technologies for air cleaning and disinfection?

Some emerging technologies for air cleaning and disinfection include bipolar ionization, photocatalytic oxidation, and nanofiltration. These technologies are still being researched and developed, but show promise for improving air cleaning and disinfection effectiveness. For example, bipolar ionization has been shown to be effective against airborne viruses and bacteria, while photocatalytic oxidation has been shown to be effective against volatile organic compounds (VOCs) and other airborne pollutants.

What considerations should be taken when selecting air cleaning and disinfection technologies for existing buildings?

When selecting air cleaning and disinfection technologies for existing buildings, care and professional judgment should be taken to understand the pros and cons of each technology, as well as their impact on existing building systems. Factors to consider include the type and size of the building, the number of occupants, the type of airborne pathogens present, and the existing HVAC system design and operation. It is also important to consult with experts in the field and follow guidance from reputable organizations, such as ASHRAE.